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Finding the Significance of Indican in Urine Test

Friday, October 12th, 2012

Intestinal toxemia and other digestive problems are best diagnosed after an Indican urine test or the Obermeyer test. When amino acid and intestinal bacteria react, it produces the indole known as Indican which is excreted in the urine normally in small amounts.

However, inadequate and inefficient digestion of protein can lead to an increase in the amount of indicant in the urine as shown by medical testing. Excessive Indican urine test results can come from the following conditions:

Liver Dysfunction

Proteins that are not properly metabolized by the intestines and the liver will ultimately lead to indoles. Simply said, digestion issues can lead to problems in your Indican urine test results. Laboratory workers will be able to get the indicant level only after reagents are combined with your urine sample. It is impossible to pass a urine test if large amounts of indicans are found on the urine which could only mean gastrointestinal toxicity.

Poor protein absorption

The improper transport of amino acids in the kidneys and intestines can result to Hartnup Disease which is usually manifested in the skin and brain. Stress, drugs or mere sunlight can trigger the symptoms of the disease. The maldigestion of protein can have ill effects on:

  • Gut dysbiosis
  • Water and hormone balance
  • Glycemic control

Overgrowth of bacteria in the intestine

Malnutrition can develop when bacterial concentration in the small bowel is too high. Bacterial overgrowth can also lead to macrocytic anemia and diarrhea among other symptoms of gastroenterologic problems like parasitic and fungal infections in the intestine and obstruction in the intestine.

What is an Indican urine test?

This is an efficient medical testing procedure that makes use of a urine sample to diagnose the levels of indican. The test is conducted by treating urine with chloroform and an Obermeyer reagent consisting of ferric chloride and hydrochloric acid. A clear solution means you pass the urine test. But if it turns into indigo or becomes opaque then the result is positive.

The urine sample is perhaps the easiest body fluid that can be obtained but it is not often considered an important tool for the diagnosis of an illness. Even experienced doctors usually give a superficial glance to the result of a urine test but not when it comes to an Indican urine test.

There are many reasons why an Indican urine test could become positive including too much or maldigestion of protein. It can also be caused by obstructions in the bile duct caused by gallstones. The result of the test can thus be used by your doctor to treat you or get further tests to confirm his medical diagnosis.

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